Officers were called to Ninth and Market at 7:47 p.m., responding to reports of a man assaulting a woman. A witness told officers that when they approached the two, the man ran off.
Police arrived with the fire department, who started life-saving treatment on the 37-year-old woman, but she died from her injuries.
The man returned about an hour later, and officers arrested him.
Detectives are investigating this case as a homicide. It is unknown what led up to the attack.